Stress-induced cardiovascular responses to cold pressure test in healthy young subjects

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Valeri Nikolov
Miroslava Petkova
Emil Nikolov


Hypertension is one of the leading diseases of the cardiovascular system. It is manifested by changes in arterial stiffness. Cardiovascular reactivity, especially blood pressure (BP), changes during the cold pressor test (CPT) depending on various factors. Undoubtedly, stress is one of the most important factors. The aim of the study is to investigate the various effects of CPT on cardiovascular responses in healthy young subjects. 56 healthy individuals aged between 21 and 26 years have been investigated. The Cardiovascular responses (BP, heart rate, aortic pulse wave velocity) to CPT were recorded by using the applanation tonometry. The Medical Outcomes Study Sleep Scale and the State-Trait Anxiety Inventory were assessed. 32,14%(n=18) of individuals who had showed difference in systolic BP more than 22 mm of Hg and difference in diastolic BP more than 18 mm of Hg after the CPT were defined as hyperreactors. Hyperreactors showed a significantly higher increase in sleep disturbances (P > 0.01) and anxiety when compared to the normoreaktors. The CPT used to diagnose cardiovascular reactivity in young individuals and the assessment of perceived stress can help identify candidates for a future risk of hypertonic disease.


Keywords: Cold pressor test; cardiovascular reactivity; applanation tonometry; blood pressure; stress


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Nikolov, V., Petkova, M., & Nikolov, E. (2021). Stress-induced cardiovascular responses to cold pressure test in healthy young subjects. Global Journal of Psychology Research: New Trends and Issues, 11(2), 70–80.